Wednesday, April 09, 2008

Hope Renewed...


Ms. F lived. She beat the odds. She was found unresponsive at home covered in her own feces, surrounded by flies and maggots. No one knew how long she had been in this state. She was having trouble breathing and was put on a breathing machine as she was transported to our emergency department. Her temperature on presentation was 94.0, her respiratory rate was 40, her heart rate was 130, and her blood pressure was 80/40. She was completely unresponsive, even to painful stimuli. She was bleeding from every orifice except her eyes and ears. Her labs on admission showed a white count of 2.0, a hemoglobin of 5.0, and a platelet count of 10. Her BUN was 255 and her Creatinine was 10! All of here electrolytes were abnormal.

She was infected, her mental status was horrible, she was having trouble maintaining an adequate blood pressure, she required the support of a breathing machine, her kidneys were shutting down, and she was bleeding profusely.

Ms. F has a history of multiple sclerosis and her only other hospitalization had been for renal failure secondary to a neurogenic bladder. It turns out that this time she had also been experiencing decreasing urine output over the prior week or two. She had difficulty urinating and toxins built up that resulted in altered mental status. A CT scan done the night she came in to the hospital showed that she had retained so much urine that she had perforated her bladder.

Ms. F was on a ventilator for ~ 15 days. She received 15 units of blood and platelets over the first 2-3 days she was in the MICU. She was treated with very broad spectrum antibiotics. She underwent bladder repair.


She lived. She left the hospital a few days ago. She has two little kids at home. I met one of them -- a wide-eyed seven year old who will probably never know how close he came to losing his mom.


When she first came into the hospital, I had no idea if she would live. I thought for sure that she would pass away. Her recovery speaks to the strength of youth and the remarkable ability of the MICU nurses to deliver fantastic care.

Cases like hers remind me of advice that one of my surgery attendings once gave me. We had just left a patient's room where he had discussed the pros and cons of getting lung surgery to remove a tumor. The patient had asked my attending how long he had to live. As we left the room, my attending turned to me and said "Never be arrogant enough to think you know how long a patient has. You will always be wrong! Anything you say is a guess... an educated guess but a guess nonetheless."

So much of what we do involves predicting mortality. When a patient asks if he should undergo surgery or when the family asks how likely it is that their loved one will get off of the ventilator, they are really asking what their chances of dying are... And I don't know.

Ms. F was the exception. The next 99 people who come in with her problems will probably die in the hospital within a few days. The question is, do we treat those other 99 people just as aggressively in the hope that they turn around like Ms. F did? Or, do we tell the family that the chances of recovery are so small that they should make the patient comfortable and not pursue aggressive treatment?